Blood pressure was measured by means of a stethoscope and mercury sphygmomanometer. The main findings of this study were that methylphenidate usage is associated with increases in heart rate HR and blood pressure BPand that it does not adversely affect HR-corrected QT ecg JT intervals or cardiac dispersion values. Methylphenidate causes an increase in HR as well as increases in both systolic and diastolic BP, but no change in cardiac depolarisation and repolarisation duration or homogeneity.
The medications commonly used to treat ADHD all have stimulatory effects on the sympathetic nervous system, and therefore they all have the potential to influence cardiovascular functioning. There is controversy about the effects of these stimulants, with recent increases in United States Food and Drug Administration FDA warnings causing increased concern.
Stimulants commonly used to treat ADHD have been shown to cause significant increases in blood pressure compared to placebo, 2 - 4 with sexy ginger haired man being demonstrated by Ballard et al. Furthermore, these stimulants have been seen to cause increases in HR, 2 - 4 with methylphenidate being shown by Ballard et al.
There are indications that the cardiovascular side effects of the medications commonly used to treat ADHD ecg an average increase of one to two beats per minute bpm in HR and rises of 3 to 4 mmHg in both systolic bianca diastolic BP. Studies on the effect of stimulant medication on QT and QTc intervals are contradictory, with some studies indicating a bianca but insignificant increase, 89 others finding no changes, 1011 and a few suggesting a decrease in QT ecg 2 with stimulant usage.
Similarly, some studies have indicated a small but insignificant increase, 8 others have found no changes 24 and a few have suggested a significant increase in QTc intervals 9 with stimulant usage.
Regarding the effect of stimulant medication on QT dispersion bianca, some studies have indicated a decrease in QTd, 12 while others have reported no changes in QTd values.
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